Heart disease remains the leading cause of death worldwide, with coronary artery disease (CAD) being the most common form. Early detection is crucial for preventing severe complications such as heart attacks. Coronary CT angiography (CTCA) has emerged as a game-changing, non-invasive imaging technique that helps diagnose coronary artery disease before it becomes life-threatening.

Advancements in radiology imaging now allow for high-quality scans with reduced radiation exposure, making it an essential tool for diagnosing, managing, and monitoring heart disease. According to Dr Vishesh Sood, a diagnostic radiologist at SCP Radiology, “Radiology plays a pivotal role in detecting and managing coronary artery disease, enabling early intervention and better patient outcomes.”

What is coronary artery disease?

Coronary artery disease is the gradual narrowing of the coronary arteries, which supply blood to your heart.

What causes this narrowing?

It is caused by plaque building up in the inner lining – a process known as atherosclerosis. Plaque is made up of deposits of varying degrees of fatty substances, cholesterol, cellular waste products, calcium, and fibrin. As it builds up in the arteries, the artery walls become progressively thickened and stiff.

What happens when this buildup occurs?

These signs and symptoms of coronary artery disease occur when the heart doesn’t get enough oxygen-rich blood. Reduced blood flow to the heart can cause a wide range of symptoms, most commonly chest pain (angina) and shortness of breath. A complete blockage of blood flow can cause a heart attack, which means that blood flow to a part of the heart is reduced for a long enough time and the heart muscle is permanently damaged or dies.

What are the risk factors you CAN control?

• High blood pressure
• Elevated cholesterol levels
• Smoking
• Diabetes
• Overweight or obesity
• Lack of physical activity
• Unhealthy diet and stress

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What you can’t control

However, it’s important to note that genetics also play a crucial role in determining an individual’s risk level. Managing coronary artery disease involves adopting lifestyle changes such as a healthy diet, regular exercise, and quitting smoking, along with medications like statins to lower cholesterol. A coronary CT empowers doctors to recommend these changes and treatments, with the aim of preventing serious cardiovascular events.

How long does this condition take to develop?

Coronary artery disease generally progresses gradually over decades. The disease may go entirely unnoticed until a significant blockage causes problems or a heart attack occurs.

‘Which is why,’ says Dr Sood, ‘we advocate the use of coronary CT angiography, the most sensitive imaging method to confirm the disease.’

He says, ‘This is particularly important in patients with non-specific symptoms, for example chest pain, which could be caused by a range of problems like musculoskeletal issues, gastrointestinal conditions or even anxiety. In these instances, coronary CT angiography is an excellent non-invasive test to confirm whether high levels of plaque are present in the coronary arteries.’

What is Coronary CT angiography?

It produces detailed images of the heart for precise evaluation of the coronary arteries. A contrast dye is injected into a vein (usually in the arm) before imaging, to increase the visibility of any obstructions in the coronary arteries.

The advantages of a Coronary CT angiography

It provides high resolution images of the coronary arteries, during a short, non-invasive procedure.

The disadvantages of a Coronary CT angiography

Even though CTCA provides detailed images of the coronary arteries, it does not allow for interventions, such as inserting a stent during the same procedure. It is used primarily for diagnosis.

Dr Sood says, ‘This is not the only method for detecting coronary artery disease. The diagnostic ‘gold standard’ has always been coronary or catheter angiography.’

What is a coronary catheter angiography?

During this procedure, a catheter is threaded through blood vessels to the coronary arteries and a contrast dye is injected to make the arteries visible on X-ray images.

The advantages catheter angiography

It allows for detailed analysis of the blood flow within the coronary arteries. If a balloon needs to be inserted to stretch open a narrowed or blocked artery, it can be done at the same time. ‘Although’, says Dr Sood, ‘the more popular choice is to insert a permanent stent to allow blood to flow more freely, which can also be performed during coronary angiography.’

The disadvantages catheter angiography

It is an invasive procedure. Threading a catheter through blood vessels, usually from the groin or wrist, up to the coronary arteries can be uncomfortable for patients. It may take an hour or longer to complete and may result in bleeding, infection and some potential damage to blood vessels. 

Who makes the decision to perform a Coronary CT?

The specialist will do a thorough assessment and then makes the decision. ‘The choice between cardiac CT and angiogram depends on the specific situation, the information needed and individual patient factors,’ explains Dr Sood. ‘Cardiac CT is often used for initial screening or non-invasive assessment, while conventional coronary angiography is usually for cases where more detailed information about the blood flow is required or when the plan is to insert a balloon or stent into the artery to expand it.’

CTCA is quickly becoming a cornerstone in modern cardiology to detect coronary disease that can be detected and managed before it becomes life-threatening.

• This article is intended to create awareness and none of the information it contains should replace the need for seeking personal advice from a qualified medical practitioner.

• Apart from selected screening examinations, all radiology procedures are performed upon referral from a qualified medical professional.